Cognitive Reflection Test (CRT) Practice

What important information should a nurse relay to a client and family about donepezil, prescribed for mild dementia?

1. Serious side effects will require immediate hospitalization

2. Blood tests that reflect liver function will be performed routinely

3. The medication should be taken on an empty stomach

4. The medication may cause an increase in appetite

The correct answer is: Blood tests that reflect liver function will be performed routinely

The correct choice emphasizes the necessity of routine blood tests to monitor liver function while a patient is on donepezil. This is important because donepezil, which is used to treat mild to moderate dementia related to Alzheimer's disease, can affect liver enzymes in some individuals. Regular monitoring allows healthcare providers to detect any potential liver issues early and adjust treatment as necessary to ensure the patient's safety. The rationale behind choosing this answer lies in the nature of donepezil's pharmacokinetics and the need for vigilance regarding side effects that may not be immediately apparent to the patient or family. Notably, while donepezil is generally well-tolerated, understanding and monitoring for any liver-related complications is crucial to maintaining the patient's overall health during treatment. In contrast, information about serious side effects requiring hospitalization tends to be less common with donepezil, as most patients do not experience such severe reactions. Requiring the medication to be taken on an empty stomach is not applicable to donepezil, as it can be taken with or without food without significantly affecting its efficacy. Additionally, donepezil is more likely to result in gastrointestinal side effects, such as nausea, rather than causing an increase in appetite. Therefore, the critical focus should remain on the necessity